Last Update 1998.12.15


南  享

Toru MINAMI

物質工学科、物質合成化学講座
分子設計研究室、教授

出身校又は最終学歴

大阪大学大学院工学研究科博士課程応用化学専攻:工学博士(大阪大学)

所属学会等

日本化学会、有機合成化学協会、American Chemical Society

研究テーマ

(1)α−ケトビニルリン試剤を用いるキナン類の新合成

(2)モノテルペン修飾基を有するビニルリン化合物の開発とセスキテルペン類の新合成

(3)α−メタロビニルリン化合物の創製と利用

(4)酸性修飾基を有する新不斉ホスフィン配位子の構築と不斉触媒反応への利用

発表論文リスト(1992以降)

 

1. T. Minami and J. Motoyoshiya, Vinylphosphonates in Organic Synthesis, Synthesis, 1992, 333-349.

2. Y. Okada, T. Minami, T. Yamamoto, and J. Ichikawa, A Novel Type of Chiral Diphosphine Ligand, trans-2,3-Bis(diphenylphosphino)-1-methyl-1-cyclopropanecarboxylic Acid and Asymmetric Allylic Alkylation by the Use of Its Palladium Complex, Chem. Lett., 1992, 547ミ550.

3. J. Ichikawa, T. Minami, T. Sonoda, and H. Kobayashi, A Facile Synthesis of Disubstituted 1,1-Difluoro-1-alkenes via Double Transmetalation of 2,2-Difluorovinylboranes, Tetrahedron Lett., 33, 3779-3782 (1992).

4. J. Ichikawa, C. Ikeura, and T. Minami, A New Synthesis of 1,1-Difluoro-1,3-dienes via the Coupling Reaction of 2,2-Difluorovinylboranes, Synlett, 1992, 739-740.

5. J. Ichikawa, S. Yonemaru, and T. Minami, A Novel Synthesis of 2,2-Difluorovinyl- and 2-Fluorovinylphosphorus Compounds from 2,2,2-Trifluoroethyl p-Toluenesulfonate, Synlett, 1992, 833-834.

6. M. Yasuda, T. Kishi, C. Goto, H. Satoda, K. Nakabayashi, T. Minami, and K. Shima, Efficient Cross-Photocycloadditions of 3-Vinylcoumarins to Olefins, Tetrahedron Lett., 33, 6465-6468 (1992).

7. J. Ichikawa, N. Yokota, M. Kobayashi, and T. Minami, The Reaction of Fluorovinyl Ketones with Carbon Nucleophiles: A New, General Route to a,b-Unsaturated Ketones, Synlett, 1993, 186-188.

8. J. Ichikawa, C. Ikeura, and T. Minami, A One-pot Synthesis of Conjugated Fluoroenynes via 2,2-Difluorovinylcopper Intermediates, J. Fluorine Chem., 63, 281-285 (1993).

9. T. Minami, M. Kamitamari, T. Utsunomiya, T. Tanaka, and J. Ichikawa, Synthesis of Annulated g-Lactams via Intramolecular 1,3-Dipolar Cycloadditions of Functionalized N-Allyl a-Diazo Amides, Bull. Chem. Soc. Jpn., 66, 1496-1500 (1993).

10. T. Minami, T. Isonaka, Y. Okada, and J. Ichikawa, Copper(I) Salt-Mediated Arylation of Phosphinyl-Stabilized Carbanions and Synthetic Application to Heterocyclic Compounds, J. Org Chem., 58, 7009-7015 (1993).

11. Y. Okada, T. Minami, and J. Ichikawa, A Novel Type of Chiral Diphosphine Ligand, trans-2,3-Bis(diphenylphosphino)-1-methyl-1-cyclopropanecarboxylic Acid and Asymmetric Allylic Alkylation by the Use of Its Palladium Complex, Phosphorus, Sulfur, and Silicon, 77, 153 (1993).

12. J. Ichikawa, M. Kobayashi, N. Yokota, Y. Noda, and T. Minami, Reaction of 2,2-Difluorovinyl Ketones with Heteroatom Nucleophiles: A General One-Pot Synthesis of a-Oxoketene Acetals, Tetrahedron, 50, 11637-11646 (1994).

13. T. Minami, T. Utsunomiya, S. Nakamura, M. Okubo, N. Kitamura, Y. Okada, and J. Ichikawa, Intramolecular Ene Reaction of Vinylphosphonates. Synthetic Application to Bicyclic Compounds and Cadalane and Valerenic Acid Terpenoid, J. Org Chem., 59, 6717-6727 (1994).

14. J. Ichikawa, S. Miyazaki, M. Fujiwara, and T. Minami, Fluorine-Directed Nazarov Cyclizations: A Controlled Synthesis of Cross-Conjugated 2-Cyclopenten-1-ones, J. Org Chem., 60, 2320-2321 (1995).

15. Y. Okada, T. Minami, M. Miyamoto, T. Otaguro, S. Sawasaki, J. Ichikawa, Construction of a-Phosphonolactams via Rhodium (II)-Catalyzed Intramolecular C-H Insertion Reaction, Heteroatom Chem., 6, 195-210 (1995).

16. T. Minami and K. Okuma, "The Synthesis of Vinyl- and Aryl-phosphorus Derivatives," in Organic Functional Group Transformations, Synthetic Routes and Molecular Architecturein Organic Chemistry, eds. by A. R. Katritzky, O. Meth-Cohn, and C. W. Rees, Pergamon Press, Oxford, Chapter 2.16, 1995.

17. J. Ichikawa, M. Kobayashi, Y. Noda, N. Yokota, K. Amano, and T.Minami, Regiocontrolled Synthesis of 3- or 5-Fluorinated Pyrazoles from 2,2-Difluorovinyl Ketones, J. Org. Chem., 61(8), 2763-2769 (1996).

18. J. Ichikawa, N. Yokota, M. Kobayashi, K. Amano, and T. Minami, The Reaction of 2,2-Difluorovinyl Ketones with Amines: A Facile Method for Preparation of a-Oxoketenimines and Acetoacetylation of Amines, Synlett, 1996, 243-246.

19. T. Minami, Y. Okada, T. Otaguro, S. Tawaraya, T. Furuichi, and T. Okauchi, Development of Chiral Phosphine Ligands Bearing a Carboxyl Group and Their Application to Catalytic Asymmetric Reaction, Tetrahedron: Asymmetry, 6(10), 2469-2474 (1996).

20. T. Minami, T. Okauchi, H. Matsuki, M. Nakamura, J. Ichikawa, M. Ishida, Synthesis and Synthetic Application of Phosphonoketene Dithioacetals. New Synthesis of Dithioallenes and (a-Dithiocarboxyvinyl)phosphonates, J. Org. Chem., 61(23), 8132-8140 (1996).

21. J. Ichikawa, M. Fujiwara, H. Nawata, T. Okauchi, and T. Minami, Novel 2,2-Difluorovinylzirconocene: A Facile Synthesis of Monosubstituted gem-Difluoroolefins via Its Cross-Coupling Reaction, Tetrahedron Lett., 37(48), 8799-8802 (1996).

22. J. Ichikawa, Y. Wada, T. Okauchi, and T. Minami, 5-endo-Trigonal cyclization of o-substituted gem-difluorostyrenes: Syntheses of 2-fluorinated indoles, benzo[b]furans, and benzo[b]thiophenes., Chem. Commun., 1997, 1537-1538.

23. T. Okauchi, T. Kakiuchi, N. Kitamura, T. Utsunomiya, J. Ichikawa, and T. Minami, Lewis Acid-Catalyzed Intramolecular [2+2] Cycloaddition of a-EsterミSubstituted Conjugated Dienyl- and Trienylphosphonates. New Synthesis of Functionalized Cyclic Terpenoids, J. Org. Chem., 62(24), 8419-8424 (1997).

24. T. Okauchi, T. Fukamachi, F. Nakamura, J. Ichikawa, T. Minami, 2-Phosphono-1,1,4,4,-tetrathio-1,3-butadienes. Synthesis and Synthetic Application to Highly Functionalized Dienes and Heterocycles, Bull. Soc. Chim. Belg. 106, 525-532 (1997).

25. T. Minami, Asymmetric Synthesis: Graphical Abstracts and Experimental Methods, eds. by T. Hayashi, K. Tomioka, and O. Yonemitsu, Kodansha, Tokyo, p. 201 (1998)

26. R. Kouno, T. Okauchi, M. Nakamura, J. Ichikawa, T. Minami, Synthesis and Synthetic Utilization of a-Functionalized Vinylphosphonates Bearing b-Oxy or b-Thio Substitutents, J . Org. Chem., 63(18), 6239-6246 (1998).

27. T. Minami, Reactive Organometallics, eds. by S. Murahashi, Y. Moro-oka, and A. Yamamoto, Kodansha, Tokyo, p. 223 (1998).

28. J. Ichikawa, M. Fujiwara, T. Okauchi, T. Minami, Fluorine-Directed Nazarov Cyclizations 2: Regioselective Synthesis of 5-Trifluoromethyl-2-cyclopentenones, Synlett, 1998(8), 927-929.

29. T. Okauchi, T. Yano, T. Fukamachi, J. Ichikawa, T. Minami, Phosphonovinyl Nonaflate: Their Synthesis and Cross-Coupling Reactions, Tetrahedron Lett., 40(29), 5337-5340 (1999).

30. J. Ichikawa, H. Jyono, S. Yonemaru, T. Okauchi, T. Minami, A Facile Synthesis of 1-H-2,2-Difluorovinylphosphorus Compounds from 2,2,2-Trifluoroethyl Trifluoromethanesulfonate and Substitutions of Their Vinylic Fluorines, J. Fluor. Chem., 97, 109-114 (1999).

31. M. Fujiwara, J. Ichikawa, T. Okauchi, T. Minami, Vinylic C-F Bond Activation: Generation and Cross-Coupling Reactions of 1-Fluorovinylzirconocene, Tetrahedoron Lett., 40(40), 7261-7265 (1999).

32. T. Minami, R. Kouno, T. Okauchi, M. Nakamura, J. Ichikawa, Synthetic Utilization of a-Phosphonovinyl Anions, Phosphorus, Sulfur and Silicon, 144-146, 689-692 (1999).

33. T. Okauchi, H. Nagamori, R. Kouno, J. Ichikawa, and T. Minami, Synthesis of 5-Diphenylphosphinoly-2,3-dihydropyran-4-ones, Heterocycles, 53(3), 1393-1398 (2000).

34. T. Okauchi,M. Itonaga,T. Minami, T. Owa, K. Kitoh, and H. Yoshino, General Method for Acylation of Indoles at the 3-Position with Acyl Chlorides in the Presence of Dialkylaluminum Chloride, Organic Lett., 2(10), 1485-1487 (2000).

35. T. Okauchi, K. Fujita, T. Ohtaguro, S. Ohshima, and T. Minami, Asymmetric Allylic Alkylation of Cycloalkenediol Diacetates Using a Chiral Phosphine Ligand Bearing a Carbonyl Group, Tetrahedron: Asymmetry, 11(6), 1397-1403 (2000).

36. R. Kouno, T. Tsubota, T. Okauchi, and T. Minami, Synthesis and Synthetic Application of a-Formylvinylphosphonates. Facile Synthesis of Phosphono-Substituted Heterocyclic Compounds, J. Org. Chem. 65(14), 4326-4332 (2000).

37. J. Ichikawa, M. Fujiwara, Y. Wada, T. Okauchi, and T. Minami, The nucleophilic 5-endo-trig cyclization of gem-difluoroolefins with homoallylic functional group: syntheses of ring-fluorinated dihydroheteroaromatics, Chem. Commun., 2000, 1887-1888.



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